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Bio-identical Hormone Therapy vs. Traditional Non-Bio-identical Hormone Therapy

When a woman goes through menopause, she experiences a variety of uncomfortable symptoms due to the lack of natural hormones in her body. One of the hormones that must be balanced within a woman’s body as they age is estrogen. With hormone replacement therapy, the natural estrogen levels in a woman’s body can be restored, helping to relieve the symptoms of menopause such as hot flashes, night sweating, vaginal dryness, dry skin and eyes, essentially restoring the body to a more premenopausal state.

Differences Between Bio-identical and Non-Bio-identical Hormones

Bio-Identical Hormone TherapyBio-identical hormones have an identical molecular makeup as the hormones our bodies already produce or were producing before menopause. They work more effectively because the body can interpret and understand what is entering it versus a pharmaceutical that has a different molecular makeup than the body providing:

  • More effective symptom relief
  • Fewer side effects
  • A lower dose (resulting in less exposure to hormones–a concern for some patients and referring doctors)

For example, the Follicle Stimulating Hormone (FSH) increases estrogen levels and stimulates ovulation in premenopausal women. In peri-menopause/menopause, with the loss of estrogen, the FSH levels can rise drastically in an attempt to try to make the body produce estrogen, which it either can’t do effectively or can’t do at all.  When you add bio-identical estrogen into the body, the FSH understands that type of estrogen and begins to drop, relieving vasomotor symptoms fast and effectively.

When a non-bio-identical estrogen, such as oral estradiol, enters the body, the FSH doesn’t fully understand what is coming into the body and does not know to drop its levels like with bio-identical estrogen.

Side Effects of High Estrogen Doses

Because non-bio-identical estrogens don’t work as effectively to relieve symptoms, providers will often continue increasing estrogen doses to try to alleviate symptoms which can increase side effects and hormone exposure.

Women can experience a variety of symptoms when exposed to higher doses of estrogen, including:

  • Nausea
  • Headaches
  • Breast tenderness
  • Fluid retention
  • Mood instability
  • Vaginal bleeding


With bio-identical estrogen, a little goes a long way

A patient on a bio-identical estrogen can be on a dose of 0.5-2 mg estradiol injection q 1-2 weeks or 6 mg estrogen pellet q 3 months, whereas most women are on 1-2 mg oral estradiol q day, producing higher levels of estrogen in their body, resulting in more side effects, without effectively dropping the FSH to alleviate the symptoms. Patients who are on bio-identical estrogen report symptom relief and fewer side effects which is also reflected in their lab work.

Lab work of patients who are on non-bio-identical estrogen show elevated estrogen levels along with an elevated FSH. When the labs are drawn 3-6 months later, depending on the form of therapy, their estrogen levels will often be lower, reducing the side effects along with a significantly decreased FSH which relieves symptoms.

Benefits of Naturally Restoring Hormones

Our treatments enable our patients to age healthily and experience their highest functioning body.  Maintaining optimal hormone levels alleviate the symptoms of menopause (listed above) and makes you more resilient to age-related diseases (heart disease, stroke, osteoporosis, Alzheimer’s disease, cancer, etc.).


The Midwest Hormone Centers employs a philosophy of aggressive empathy in patient care. We understand the negative impact of aging and our work is to reverse as much of those unnecessary and negative age related issues.  Our primary focus is to restore the hormonal deficiencies in our bodies utilizing bio-identical hormones. Simply stated, we put back in our bodies those things our bodies used to produce. Natural hormones are identical to the hormones already found in your body and follow the blue print of human life. Your body receives these hormones as if they were made by your own organs. Our treatment is customized for each patient and ensures optimization of patients well being and vitality.


Take our Female Hormone Assessment or call Midwest Hormone Centers today to learn more!

I love this place! Midwest offers a wide range of services that help their patients achieve optimal health. I have been a patient with Midwest since 2017. The testing and therapies offered helped me lose weight and increase my energy level. The staff at Midwest is great too. The ladies working their are both thorough and professional, always addressing any of my issues. They are also very caring which is one of the reasons why I recommended this place to all of my friends.
L.J. Con
L.J. Con
13:51 12 Aug 19
This place is great. Have been going here once a week for over 2 years and couldn't be happier. I'd suggest any man over 35 to get their levels checked, it can make a huge difference. Friendly professional staff - 5 stars
Kent Hill
Kent Hill
18:14 13 Aug 19
Lots of Greats; great location, great staff, and great service! Only problem I see is I can’t give them more than 5 stars! I feel amazing and rejuvenated after I leave my appointment.
JJG Ellison
JJG Ellison
16:28 14 Aug 19
I feel so good since starting testosterone and my body has changed so much. I have lost weight and have so much more energy. The girls in this office are amazing.
Kory Sheldon
Kory Sheldon
17:55 13 Aug 19
This company is not only professional, but caters to each clients specific journey; creating therapy, healing and optimization opportunities to that individuals health and whole wellness. Would recommend this practice as their culture and brand reflect how we do business at Midwest Tinting.
Midwest Tinting LS
Midwest Tinting LS
13:50 08 Jul 19
This place is so amazing they have the best humor I have ever heard. Highly recommend.
Barb Baldridge
Barb Baldridge
18:15 13 Aug 19
Midwest Hormone Centers in Leawood is hands down the best at what they do!! I highly recommend them to anyone who is interested in getting in better shape, having more energy, having better concentration and basically feeling like a million bucks! The staff is very knowledgeable and friendly and always answers your questions in a way a layperson can understand. I must say the nurses are the absolute best and they always keep me laughing and motivated. Can’t say enough positive about this place!
Wade Walters
Wade Walters
19:50 19 Sep 19

Our Offices and the neighborhoods we serve

Leawood Office

  • Kansas City, MO
  • Overland Park, KS
  • Kansas City, KS
  • Independence, MO
  • Lee’s Summit, MO
  • Shawnee, KS
  • Blue Springs, MO
  • Lenexa, KS
  • Hutchinson, KS
  • Leawood, KS
  • Liberty, MO
  • Raymore, MO
  • Grain Valley, MO
  • Excelsior Springs, MO
  • St. Joseph, MO
  • Warrensburg, MO
  • Merriam, KS
  • Harrisonville, MO
  • Kearney, MO
  • Pleasant Hill, MO
  • Oak Grove, MO
  • Bonner Springs, KS
  • Wichita, KS

Lawrence Office

  • Lawrence, KS
  • Gardner, KS
  • Olathe, KS
  • Topeka, KS
  • Ottawa, KS
  • Lansing, KS
  • Leavenworth, KS
  • Eudora, MO
  • De Soto, KS
  • Baldwin City, KS
  • Manhattan, KS
  • Raytown, MO
  • Gladstone, MO
  • Grandview, MO
  • Belton, MO
  • Prairie Village, KS

Louisburg Office

  • Louisburg, KS
  • Stilwell, KS
  • Paola, KS
  • Big Springs, KS
  • Midland, KS