AOD-9604, also known as Tyr-hGH Frag 176-191 has been proven to have a strong fat burning capacity, without creating a desire to overeat. It doesn’t affect blood sugar or tissue growth. (Heffernan 2001 Heffernan 2001, Ng 2000). AOD-9604 activates degradation and fat burning (oxidation), by a method that doesn’t use hGH receptor. What is extraordinary about the AOD-9604 is its ability to reduce abdominal fat stores.
AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA. AOD 9604 is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears not to affect growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone.
AOD 9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.